Pacemakers

Our groundbreaking research has allowed us to develop the world’s smallest dual chamber pacemaker¹ and the world's first AutoMRI technology to automatically adjust pacemaker settings for MRI scans², just a couple examples of our commitment to product innovation.

Healthcare Professionals Cardiac Rhythm Management Cardiac Rhythm Management Products Pacemakers

ALIZEA

Connected, yet free

Maintain excellent clinical follow-ups-remotely. Excellent longevity* in remote mode reduces the need for replacements5. Efficiently manage AF while improving clinical outcomes.

Features

  • 13 years longevity with remote monitoring and full feature set ON*
  • LBBAP – Able to provide Left Bundle Branch Area Pacing ensuring physiological pacing6
  • SafeR™ – Minimize ventricular pacing for SND and AVB patients.3,4
  • Dual Sensor – Designed to physiologically modulate heart rhythm by combining accelerometer and minute ventilation sensors
  • Sleep Apnea Monitoring** – Screen and Monitor for Sleep Apnea.
  • AUTOMRI – Making MRI scans easy and safe for pacemaker patients.
  • Bluetooth® Remote monitoring - Offer advanced patient monitoring and follow-up, providing timely alerts and detailed reports of your patient.

*13 years with SafeR mode, assuming 5% V pacing and 50% A pacing, 60 min-1, 2.5 V, 0.35 ms, 750 Ohms, Holter ON, sensors ON, Remote ON

**Not available in the USA

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Pacemakers ALIZEA DR FACE 1 1

BOREA

Connected to life’s every beat

Promote physiological pathways. The smart way to drive efficiency – remotely. Programming set-up and follow-up made easy. Connected algorithms designed to work together for improved clinical outcomes.

Features

  • LBBAP – Able to provide Left Bundle Branch Area Pacing ensuring physiological pacing6
  • SafeR™ – Minimize ventricular pacing for SND and AVB patients.3,4
  • Bluetooth® Remote monitoring - Mean efficient access to patient data that keeps the patient out of hospital.
  • AutoMRI – Making MRI scans easy and safe for pacemaker patients.
  • Dual Sensor – Designed to physiologically modulate heart rhythm by combining accelerometer and minute ventilation sensors.
This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.
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Pacemakers BOREA DR FACE 2

ENO

One with heart

World’s smallest transvenous pacemaker.1 1.5 T and 3 T full body MR conditional. Empower AF Risk Management.

Features

  • SafeRTM* – Minimize ventricular pacing for SND and AVB patients.3,4
  • Sleep Apnea MonitoringTM – Screen and Monitor for Sleep Apnea.
  • AutoMRITM – Making MRI scans easy and safe for pacemaker patients.2
  • Dual SensorTM – Designed to physiologically modulate heart rhythm by combining accelerometer and minute ventilation sensors.

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Pacemakers ENO DR Micro Port 2018 3

TEO

Break free

World’s smallest transvenous pacemaker.1 1.5 T and 3 T full body MR conditional. Therapies activated automatically at implant.

Features

  • 12 years of longevity* in 8 cc.
  • AutoMRITM – Making MRI scans easy and safe for pacemaker patients.2
  • SafeRTM – Minimize ventricular pacing for SND and AV Block patients.3,4
  • Dual SensorTM – Designed to physiologically modulate heart rhythm by combining Accelerometer and Minute Ventilation sensors.

*SafeR Mode (5% V pacing, 50% A pacing), 60 min-1, 2.5 V, 0.4 ms, 750 Ω, SENSORS ON, EGMs ON.

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Pacemakers TEO DR Micro Port 2018 4

OTO

Sense in every cc

World’s smallest transvenous pacemaker.1 1.5 T and 3 T full body MR conditional. Fast and Easy follow-up at a click of a button.

Features

  • 11.7 years longevity* in 8 cc.
  • AutoMRITM – Making MRI scans easy and safe for pacemaker patients.
  • AutoImplant Detect – Automatically activates algorithms at implant.

*DDDR Mode (50% A & V pacing), 60 min-1, 2.5 V, 0.4 ms, 750 Ω, SENSOR ON, EGMs ON, DIAGNOSTICS ON.

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Pacemakers OTO DR Micro Port 2018 5

KORA 250

Minimum Size. Maximum Outcome.

Kora 250 is designed to improve patient outcome while driving efficiency in practice.

Features

  • AutoMRITM – Making MRI scans easy and safe for pacemaker patients.
  • SafeRTM – Designed to promote intrinsic conduction in patients who need dual-chamber pacing.
  • Sleep Apnea MonitoringTM – measures respiration pauses and reduction in respiration.
  • Dual sensorTM – combines an accelerometer and a minute ventilation sensor to provide rate response closest to sinus rhythm.

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Pacemakers Kora250 6

KORA 100

Always one step ahead

Kora 100 provides the first MRI mode that automatically detects an MRI magnetic field – another innovative solution in a pacing system known for its small size, longevity, and high performance.

Features

  • AutoMRITM – Making MRI scans easy and safe for pacemaker patients.
  • SafeRTM – Designed to promote intrinsic conduction in patients who need dual-chamber pacing.
  • Sleep Apnea MonitoringTM – Measures respiration pauses and reduction in respiration.
  • Dual sensorTM – Combines an accelerometer and a minute ventilation sensor to provide rate response closest to sinus rhythm.

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Pacemakers KORA 100 7

Reply 200

Extending the boundaries in cardiovascular disease management.

Reply 200 automatically screens patients at risk of severe sleep apnea, featuring a suite of algorithms designed to prevent serious cardiovascular comorbidities.

Features

  • 12 years longevity* in only 8 cc.
  • SafeRTM – Dramatically reduces unnecessary RV pacing in all pacemaker patients, including AV block patients.3,4
  • Sleep Apnea MonitoringTM – Measures respiration pauses and reduction in respiration.
  • Dual SensorTM – Designed to physiologically modulate heart rhythm by combining accelerometer and minute ventilation sensors.

*SafeR Mode (5% V pacing, 50% A pacing), 60 min-1, 2.5 V, 0.4 ms, 750 Ω, SENSORS ON, EGMs ON.

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

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Pacemakers REPLY 200 DR Micro Port 2018 8

Reply

Natural intelligence

A pacemaker family inspired by nature.

Features

  • SafeRTM – AV Management proven to be safe and effective for all patients with bradyarrhythmia.2,3
  • 12 years longevity* in only 8 cc. The world’s smallest dual-chamber pacemaker with no compromise on longevity.1
  • Dual sensorTM – Combines an accelerometer and a minute ventilation sensor to provide rate response closest to sinus rhythm.

*SafeR Mode (5% V pacing, 50% A pacing), 60 min-1, 2.5 V, 0.4 ms, 750 Ω, SENSORS ON, EGMs ON.

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Pacemakers REPLY DR Micro Port 2018 9

Esprit

Makes your life easier

The ESPRIT family of pacemakers features a host of dedicated algorithms designed for patient safety as well as Dplus pacing mode which significantly reduces ventricular pacing.

Features

  • Dplus – Automatic AV hysteresis.
  • Lead impedance trend, A&V Autosensing, V Auto threshold.
  • SmartCheck – Automate follow-up tests at the click of a button.

Pacemakers Esprit 10
Safer

SafeRTM

SafeR allows for intelligent management of AV conduction, significantly reducing unnecessary RV pacing in all pacemaker patients, including AV block patients.1–8

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Logo Auto MRI circle blue

AutoMRITM

AutoMRI mode is the world’s first pacemaker technology capable of detecting an MRI field and automatically switching to asynchronous mode.

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Sam

SAMTM

Proactive management of comorbidities. Early detection, long-term risk reduction. 1–6

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Dual

Dual SensorTM

Twin trace is designed to physiologically modulate the heart rhythm by combining Accelerometer and Minute Ventilation sensors.

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PICTO Paper article

SafeR Pacing Mode

Unnecessary ventricular pacing increases the risk of atrial fibrillation and heart failure hospitalization. SafeR™ is an algorithm found in the current MicroPort dual chamber models and ensures 99.9% intrinsic conduction, significantly reducing unnecessary pacing. Safer™ reduces unnecessary right ventricular pacing in both Sinus Node Disease patients and unselected AV Block patients.

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PICTO Paper article

Dplus Pacing Mode

Dplus pacing mode is an automatic AV Delay hysteresis algorithm, designed to promote the spontaneous atrio-ventricular conduction. The “Acceleration” and “AVD shortening” functions can also be programmed simultaneously to better sustain the patient avoiding the sudden rate drops, for example during vaso-vagal episodes.

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PICTO Paper article

Dual Sensor

The goal of rate adaptive pacing is to provide an increase in heart rate via an increase in cardiac pacing in response to metabolic needs: this would include during periods of exercise, but also during disease states and emotional reactions. The dual sensor technology is a combination of an accelerometer and minute ventilation for efficient rate response to chronotropic incompetence. It has been designed to blend information from accelerometer and minute ventilation sensors for a more physiologic rate response.

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PICTO Paper article

Rest Rate

Rest Rate is related to rate adaptive pacing. While rate adaptive pacing increases the pacing rate to address patient demands, the rest rate algorithm uses similar data to slow the pacing rate below the programmed basic rate. In this manner, it can reproduce circadian variations without the constraint of being set by a clock schedule. In addition, rest rate has the added benefits of potentially reducing percent pacing and therefore extending battery life, and may offer patients a more physiological pacing rate.

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PICTO Paper article

Sleep Apnea Monitoring (SAM)

With the Sleep Apnea Monitoring (SAM) function, MicroPort pacemakers provide the physician with automatic screening of pacemaker patients for the risk of severe Sleep Apnea. SAM has been designed to detect, count and report abnormal breathing events during the night. These events are detected using the minute ventilation signal. This allows the calculation of respiratory disturbances over the last six months, representing sleep disordered breathing events at night.

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PICTO Paper article

Window of Atrial Rate Acceleration Detection (WARAD)

The WARAD is designed to monitor the atrial activity in order to discriminate pathological atrial waves (Atrial Fibrillation, Atrial Flutter, Atrial Tachycardias) from sinus P waves. This atrial discriminator uses atrial prematurity to trigger mode switching. Refer also to the Fallback Mode Switch Tech Corner article for more details on the Fallback Mode Switch algorithm.

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PICTO Paper article

Fallback Mode Switch

The FMS function is designed to diagnose atrial arrhythmias and manage their occurrence using the WARAD (Window of Atrial Rate Acceleration Detection): in the event of atrial arrhythmia, FMS switches from DDD(R), SafeR™(R) or Dplus(R) pacing mode to an inhibited dual- chamber pacing mode DDI(R) to avoid prolonged ventricular pacing at a high rate for the entire duration of the sustained atrial arrhythmia.

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PICTO Paper article

Automatic Implant Detection (ALIZEA BOREA CELEA)

Automaticity at Implantation allows the pacemaker to automatically detect if the device is implanted. It has been designed to provide a secure functioning of the device during implantation without prior or post implantation interrogation.

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PICTO Paper article

Automatic Implantation Detection (ENO, TEO, OTO, and previous generations)

Automaticity at Implantation allows the pacemaker to automatically detect if the device is implanted. It has been designed to provide a secure functioning of the device during implantation without prior or post implantation interrogation.

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PICTO Paper article

Anti-PMT (Pacemaker Mediated Tachycardia) algorithm

The Anti-PMT algorithm is intended to protect the patient from Pacemaker-Mediated Tachycardia (PMT) without reducing the atrial sensing capability of the device.

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PICTO Paper article

Automatic refractory periods in pacemakers

The refractory periods are time intervals starting after pacing or sensing an event in the ventricular and atrial cavities. The aim is to protect the device from multiple detections of the same contraction or post-potential detection of the spike, as well as farfield sensing or crosstalk. In MicroPort pacemakers, the absolute refractory periods are fully automatic, except one or two of them (depending on pacemaker models).

Click here to download the full article
PICTO Paper article

Right Ventricular Autothreshold
(ALIZEA BOREA CELEA)

The Right Ventricular Autothreshold (RVAT) function allows automatic adjustment of the ventricular pacing amplitude, according to a threshold test performed automatically by the device at regular intervals. The aim is to maintain automatically and periodically the ventricular capture and to adapt the ventricular pulse amplitude in order to ensure safety and to save energy.

Click here to download the full article
PICTO Paper article

Right Atrial Autothreshold
(ALIZEA BOREA CELEA)

The Right Atrial Autothreshold (RAAT) function allows automatic adjustment of the atrial pacing amplitude, according to a threshold test performed automatically by the device every day. The aim is to maintain automatically and periodically the atrial capture and to adapt the atrial pulse amplitude in order to ensure safety and to save energy.

Click here to download the full article

MICROPORT® CRM Manuals

http://www.microportmanuals.com/


Availability of select products and their functions vary by country. Please check with your representative for further information.

  1. Competition comparison across transvenous pacing systems made as of September 2020, refer to manufacturers manuals available online
  2. MicroPortMRI Solutions available at microportmanuals.com
  3. Stockburger M, et al. Safety and efficiency of ventricular pacing prevention with an AAI-DDD changeover mode in patients with sinus node disease or atrioventricular block: impact on battery longevity-a substudy of the ANSWER trial. Europace 2016;18:739–46.
  4. Stockburger M, et al. Long-term clinical effects of ventricular pacing reduction with a changeover mode to minimize ventricular pacing in general population (ANSWER study). Eur Heart J. 2015;36:151–57
  5. Boriani G, Bertini M, Saporito D, et al. Impact of pacemaker longevity on expected device replacement rates: Results from computer simulations based on a multicenter registry (ESSENTIAL). Clin Cardiol. 2018;41(9):1185‐1191. doi:10.1002/clc.23003
  6. Alizea User Manual available online at microportmanuals.com